The Vice President-elect has carried a tote by Michael Kors several times. Below, then-Senator Harris in November 2019 with the bag, in a photo shared by Kate Waters.
The piece is the Bancroft Large Pebbled Satchel ($1490), done in textured leather with polished handles. The tote measures 14″ x 13″ x 8″ and has multiple interior pockets as well as front and back slip pockets and side gussets that allow the bag to expand from a satchel to a good-sized tote.
Below you see the tote in this photo Doug Emhoff posted on Twitter.
Thank you to my friend Reynolds for another terrific ID!